Idorsia's development compounds target a number of different diseases.



Insomnia is defined as a combination of both dissatisfaction with sleep and a significant negative impact on daytime functioning. Insomnia is, worldwide, the most commonly reported sleeping disorder.

Resistant hypertension management

High blood pressure (also known as hypertension) is one of the most common medical conditions and its prevalence continues to rise. If someone’s high blood pressure can’t be lowered despite treatment with a combination of three anti-hypertensive drugs of different categories (including a diuretic), they may have resistant hypertension.

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disease that can affect the skin, joints, kidneys, brain and other organs.

Acute myocardial infarction

Most often a heart attack (myocardial infarction) happens when one of the coronary arteries that normally delivers oxygen-rich blood from the heart, through the coronary arteries, to the heart muscle (also called myocardium) becomes partially or fully blocked, usually as a result of a blood clot. This reduces or cuts off the blood flow to that part of the heart muscle and it begins to die due to a shortage of oxygen.

Fabry disease

Fabry disease is a rare inherited disorder in which a particular lipid (a fat-like substance) can’t be broken down by the body, leading to its build-up in the cells of the body organs.